Basic Information
ID: ALA1102236
Type: Binding
Description: Inhibition of human recombinant IGF-1R tyrosine kinase expressed in baculovirus system assessed as [33gamma]ATP phosphorylation of poly(Glu/Tyr) substrate after 45 mins by scintillation counting
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1102236
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 479.97 | 3.86 | 3.86 |
| 467.96 | 3.10 | 3.10 |
| 481.99 | 3.59 | 3.59 |
| 512.41 | 3.21 | 3.21 |
| 433.52 | 2.45 | 2.45 |
| 447.54 | 2.93 | 2.93 |
| 477.57 | 2.56 | 2.56 |
| 461.57 | 3.50 | 3.50 |
| 512.01 | 3.21 | 3.21 |
| 496.02 | 4.15 | 4.15 |
| 502.41 | 3.76 | 3.76 |
| 433.52 | 2.68 | 2.68 |
| 444.50 | 2.24 | 2.24 |
| 491.55 | 2.55 | 2.55 |
| 477.53 | 2.16 | 2.16 |
| 419.49 | 2.37 | 2.37 |
| 453.93 | 3.03 | 3.03 |
| 536.03 | 4.37 | 4.37 |
| 561.09 | 4.52 | 4.52 |
| 563.10 | 4.33 | 4.33 |
| 620.15 | 4.38 | 4.38 |
| 449.52 | 1.86 | 1.86 |
| 476.54 | 1.73 | 1.73 |
| 462.51 | 1.47 | 1.47 |
| 490.57 | 2.07 | 2.07 |
| 463.50 | 2.07 | 2.07 |
| 478.98 | 3.44 | 3.44 |
| 493.01 | 3.78 | 3.78 |
| 525.03 | 4.12 | 4.12 |
| 478.98 | 3.56 | 3.56 |
| 478.98 | 3.56 | 3.56 |
| 593.13 | 5.52 | 5.52 |
| 579.10 | 5.13 | 5.13 |
| 575.11 | 4.47 | 4.47 |