Basic Information
ID: ALA1102771
Type: Binding
Description: Inhibition of GST-tagged JAK1 assessed as inhibition of biotinylated IRS1 substrate phosphorylation after 60 mins by caliper mobility shift assay
Activity Charts
Bioactivity
Activity Types for Assay ALA1102771
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.40 | 4.66 | 4.66 |
| 376.41 | 5.26 | 5.26 |
| 410.86 | 5.92 | 5.92 |
| 406.44 | 5.27 | 5.27 |
| 427.46 | 5.81 | 5.81 |
| 469.52 | 4.64 | 4.64 |
| 469.52 | 4.64 | 4.64 |
| 489.53 | 4.74 | 4.74 |
| 507.52 | 4.88 | 4.88 |
| 475.55 | 5.10 | 5.10 |
| 470.53 | 4.41 | 4.41 |
| 484.56 | 4.72 | 4.72 |
| 506.55 | 5.36 | 5.36 |
| 492.53 | 5.02 | 5.02 |
| 511.63 | 4.77 | 4.77 |
| 563.65 | 5.34 | 5.34 |