Basic Information
ID: ALA1104444
Type: Binding
Description: Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillation counting
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Target: Squalene synthetase(ALA3815)
Document: ALA1156999
Inhibition of squalene synthase in rat liver microsomes assessed as conversion of [1-3H]FPP to [3H]squalene level after 60 mins by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1104444
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.23 | 0.50 | 0.50 |
| 392.24 | 1.97 | 1.97 |
| 408.24 | 1.21 | 1.21 |
| 472.31 | 0.45 | 0.45 |
| 488.30 | -0.31 | -0.31 |