Inhibition of FPPS in rat liver S10 supernatant assessed as conversion of (R,S)-[2-14C]mevalonic acid to [14C]squalene at 1 uM after 60 mins

Basic Information

ID: ALA1104445

Type: Binding

Description: Inhibition of FPPS in rat liver S10 supernatant assessed as conversion of (R,S)-[2-14C]mevalonic acid to [14C]squalene at 1 uM after 60 mins

Format: BAO_0000019

Organism: Rattus norvegicus

Target:  Farnesyl pyrophosphate synthase(ALA1075093)

Document:  ALA1156999

Inhibition of FPPS in rat liver S10 supernatant assessed as conversion of (R,S)-[2-14C]mevalonic acid to [14C]squalene at 1 uM after 60 mins: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
319.230.500.50
392.241.971.97
472.310.450.45
488.30-0.31-0.31