Inhibition of squalene synthase in rat liver S10 supernatant assessed as conversion of (R,S)-[2-14C]mevalonic acid to [14C]squalene at 10 uM after 60 ...

Basic Information

ID: ALA1104452

Type: Binding

Description: Inhibition of squalene synthase in rat liver S10 supernatant assessed as conversion of (R,S)-[2-14C]mevalonic acid to [14C]squalene at 10 uM after 60 mins

Format: BAO_0000019

Organism: Rattus norvegicus

Target:  Squalene synthetase(ALA3815)

Document:  ALA1156999

Inhibition of squalene synthase in rat liver S10 supernatant assessed as conversion of (R,S)-[2-14C]mevalonic acid to [14C]squalene at 10 uM after 60 mins: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
319.230.500.50
392.241.971.97
472.310.450.45
488.30-0.31-0.31