Basic Information
ID: ALA1104615
Type: Binding
Description: Selectivity index, ratio of IC50 for PI3Kalpha to IC50 for human mTOR
Format: BAO_0000019
Target: Unchecked(ALA612545)
Document: ALA1157009
Selectivity index, ratio of IC50 for PI3Kalpha to IC50 for human mTOR: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1104615
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 528.62 | 3.74 | 3.74 |
| 494.56 | 2.48 | 2.48 |
| 526.57 | 2.82 | 2.82 |
| 558.64 | 3.10 | 3.10 |
| 520.59 | 3.02 | 3.02 |
| 527.63 | 3.31 | 3.31 |
| 526.65 | 3.92 | 3.92 |
| 654.78 | 4.13 | 4.13 |
| 396.45 | 3.80 | 3.80 |
| 372.43 | 2.90 | 2.90 |
| 372.43 | 2.90 | 2.90 |
| 373.42 | 2.30 | 2.30 |
| 373.42 | 2.30 | 2.30 |
| 373.42 | 2.30 | 2.30 |
| 414.47 | 3.28 | 3.28 |
| 428.50 | 3.30 | 3.30 |
| 430.47 | 3.50 | 3.50 |
| 527.63 | 4.35 | 4.35 |
| 540.67 | 4.26 | 4.26 |
| 525.66 | 3.46 | 3.46 |
| 542.64 | 3.85 | 3.85 |
| 543.63 | 3.24 | 3.24 |
| 555.69 | 3.77 | 3.77 |
| 512.62 | 3.66 | 3.66 |
| 540.67 | 4.31 | 4.31 |
| 558.66 | 4.26 | 4.26 |
| 554.70 | 4.70 | 4.70 |
| 552.68 | 4.45 | 4.45 |
| 556.67 | 3.28 | 3.28 |
| 570.70 | 3.93 | 3.93 |
| 583.74 | 3.85 | 3.85 |
| 609.78 | 4.38 | 4.38 |
| 588.72 | 5.81 | 5.81 |
| 589.70 | 5.21 | 5.21 |
| 578.68 | 4.53 | 4.53 |
| 522.61 | 3.26 | 3.26 |
| 536.64 | 3.65 | 3.65 |
| 554.63 | 3.60 | 3.60 |
| 568.65 | 3.99 | 3.99 |
| 548.65 | 3.80 | 3.80 |
| 562.68 | 4.19 | 4.19 |
| 556.63 | 4.38 | 4.38 |
| 600.68 | 3.91 | 3.91 |
| 653.79 | 5.02 | 5.02 |
| 682.83 | 4.17 | 4.17 |
| 669.79 | 4.25 | 4.25 |
| 469.59 | 3.75 | 3.75 |