Basic Information
ID: ALA1105365
Type: Binding
Description: Inhibition of NF-kappaB expressed in HEK293 cells assessed as inhibition of TNF-alpha-stimulated transcriptional activation at 10 uM treated 24 hrs before TNFalpha challenge measured after 20 to 24 hrs by luciferase reporter gene assay
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1105365
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.58 | 5.62 | 5.62 |
| 500.02 | 6.27 | 6.27 |
| 522.63 | 5.58 | 5.58 |
| 543.67 | 5.02 | 5.02 |
| 511.67 | 6.34 | 6.34 |
| 466.57 | 5.01 | 5.01 |
| 479.61 | 5.93 | 5.93 |
| 514.05 | 6.58 | 6.58 |
| 557.70 | 5.33 | 5.33 |
| 525.70 | 6.65 | 6.65 |
| 480.59 | 5.32 | 5.32 |
| 514.05 | 6.58 | 6.58 |
| 536.66 | 5.88 | 5.88 |
| 557.70 | 5.33 | 5.33 |
| 539.73 | 6.25 | 6.25 |
| 480.59 | 5.32 | 5.32 |
| 479.61 | 5.93 | 5.93 |
| 514.05 | 6.58 | 6.58 |
| 536.66 | 5.88 | 5.88 |
| 557.70 | 5.33 | 5.33 |
| 539.73 | 6.25 | 6.25 |
| 480.59 | 5.32 | 5.32 |
| 495.60 | 5.63 | 5.63 |
| 573.70 | 5.03 | 5.03 |
| 496.59 | 5.02 | 5.02 |
| 573.70 | 5.03 | 5.03 |
| 573.70 | 5.03 | 5.03 |
| 501.01 | 5.67 | 5.67 |
| 500.02 | 6.27 | 6.27 |
| 534.47 | 6.92 | 6.92 |
| 557.08 | 6.23 | 6.23 |
| 578.12 | 5.67 | 5.67 |
| 501.01 | 5.67 | 5.67 |
| 507.62 | 5.82 | 5.82 |
| 542.06 | 6.47 | 6.47 |
| 585.71 | 5.22 | 5.22 |
| 508.60 | 5.22 | 5.22 |