Assay Report Card

Basic Information

ID: ALA1105654

Type: Binding

Description: Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release at 25 uM after 30 mins

Organism: Homo sapiens

Cell type: L12-G10

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
198.272.702.70
287.361.851.85
179.312.692.69
402.172.522.52
310.142.152.15
600.365.635.63
626.395.425.42
598.344.814.81
412.585.245.24
482.727.197.19
491.274.164.16
196.253.213.21
338.192.642.64
404.526.566.56
460.638.128.12
502.719.299.29
688.405.425.42
744.506.986.98
786.588.158.15
496.747.007.00
594.406.186.18
338.193.023.02
524.264.234.23
538.294.624.62
552.315.015.01
566.345.405.40
580.375.795.79
608.426.576.57
622.456.966.96
636.487.357.35
650.507.747.74
664.538.138.13
656.424.284.28