Basic Information
ID: ALA1105654
Type: Binding
Description: Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release at 25 uM after 30 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: L12-G10
Target: Glutamate NMDA receptor; GRIN1/GRIN2A(ALA1907604)
Document: ALA1157915
Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release at 25 uM after 30 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1105654
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 198.27 | 2.70 | 2.70 |
| 287.36 | 1.85 | 1.85 |
| 179.31 | 2.69 | 2.69 |
| 402.17 | 2.52 | 2.52 |
| 310.14 | 2.15 | 2.15 |
| 600.36 | 5.63 | 5.63 |
| 626.39 | 5.42 | 5.42 |
| 598.34 | 4.81 | 4.81 |
| 412.58 | 5.24 | 5.24 |
| 482.72 | 7.19 | 7.19 |
| 491.27 | 4.16 | 4.16 |
| 196.25 | 3.21 | 3.21 |
| 338.19 | 2.64 | 2.64 |
| 404.52 | 6.56 | 6.56 |
| 460.63 | 8.12 | 8.12 |
| 502.71 | 9.29 | 9.29 |
| 688.40 | 5.42 | 5.42 |
| 744.50 | 6.98 | 6.98 |
| 786.58 | 8.15 | 8.15 |
| 496.74 | 7.00 | 7.00 |
| 594.40 | 6.18 | 6.18 |
| 338.19 | 3.02 | 3.02 |
| 524.26 | 4.23 | 4.23 |
| 538.29 | 4.62 | 4.62 |
| 552.31 | 5.01 | 5.01 |
| 566.34 | 5.40 | 5.40 |
| 580.37 | 5.79 | 5.79 |
| 608.42 | 6.57 | 6.57 |
| 622.45 | 6.96 | 6.96 |
| 636.48 | 7.35 | 7.35 |
| 650.50 | 7.74 | 7.74 |
| 664.53 | 8.13 | 8.13 |
| 656.42 | 4.28 | 4.28 |