Basic Information
ID: ALA1106147
Type: Functional
Description: Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in the presence of 50% human serum
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Calcitonin gene-related peptide type 1 receptor(ALA3798)
Document: ALA1156995
Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in the presence of 50% human serum: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1106147
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.50 | 1.84 | 1.84 |
| 460.45 | 0.41 | 0.41 |
| 480.48 | 1.78 | 1.78 |
| 426.48 | 2.73 | 2.73 |
| 446.51 | 4.10 | 4.10 |
| 468.47 | 1.37 | 1.37 |
| 488.51 | 2.74 | 2.74 |
| 482.50 | 1.39 | 1.39 |
| 502.53 | 2.76 | 2.76 |
| 453.50 | 2.70 | 2.70 |
| 473.54 | 4.06 | 4.06 |
| 467.53 | 2.87 | 2.87 |
| 487.56 | 4.24 | 4.24 |
| 481.56 | 3.26 | 3.26 |
| 501.59 | 4.63 | 4.63 |