Basic Information
ID: ALA1106186
Type: Binding
Description: Inhibition of NF-kappaB expressed in HEK293 cells assessed as inhibition of TNF-alpha-stimulated transcriptional activation treated 24 hrs before TNFalpha challenge measured after 20 to 24 hrs by luciferase reporter gene assay
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1106186
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 480.59 | 5.32 | 5.32 |
| 573.70 | 5.03 | 5.03 |
| 496.59 | 5.02 | 5.02 |
| 573.70 | 5.03 | 5.03 |
| 501.01 | 5.67 | 5.67 |
| 501.01 | 5.67 | 5.67 |
| 508.60 | 5.22 | 5.22 |