Assay Report Card

Basic Information

ID: ALA1106189

Type: Functional

Description: Inhibition of LPS-stimulated NF-kappaB activation in transgenic FVB mouse assessed as decrease in NF-kappaB activity at 50 mg/kg, po QD for 3 days before LPS challenge measured after 3 hrs by bioluminescence based luciferase reporter gene assay relative to control

Organism: Mus musculus

Strain: FVB

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
508.605.225.22