Effect on human MDR1-mediated drug transport assessed as efflux ratio of permeability from basolateral to apical side to apical to basolateral side

Basic Information

ID: ALA1106243

Type: ADME

Description: Effect on human MDR1-mediated drug transport assessed as efflux ratio of permeability from basolateral to apical side to apical to basolateral side

Format: BAO_0000357

Organism: Homo sapiens

Target:  P-glycoprotein 1(ALA4302)

Document:  ALA1156223

Effect on human MDR1-mediated drug transport assessed as efflux ratio of permeability from basolateral to apical side to apical to basolateral side: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
375.423.633.63
365.392.152.15
379.422.372.37