Basic Information
ID: ALA1106435
Type: Binding
Description: Inhibition of thymidylate synthase
Format: BAO_0000357
Target: Thymidylate synthase(ALA1952)
Document: ALA1157058
Inhibition of thymidylate synthase: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1106435
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.49 | 2.31 | 2.31 |
| 479.49 | 1.87 | 1.87 |
| 452.47 | 1.92 | 1.92 |
| 476.49 | 1.92 | 1.92 |
| 467.48 | 1.70 | 1.70 |
| 453.46 | 1.31 | 1.31 |
| 454.44 | 0.71 | 0.71 |
| 453.46 | 1.31 | 1.31 |
| 477.48 | 1.31 | 1.31 |
| 485.47 | 1.65 | 1.65 |
| 444.47 | 1.95 | 1.95 |
| 438.44 | 1.89 | 1.89 |
| 494.48 | 2.06 | 2.06 |
| 470.46 | 2.05 | 2.05 |
| 470.46 | 2.05 | 2.05 |
| 538.56 | 3.28 | 3.28 |
| 530.46 | 2.63 | 2.63 |
| 480.45 | 1.75 | 1.75 |
| 510.48 | 1.76 | 1.76 |
| 492.49 | 1.62 | 1.62 |
| 484.48 | 2.47 | 2.47 |
| 502.47 | 2.42 | 2.42 |
| 504.54 | 2.73 | 2.73 |
| 492.49 | 1.10 | 1.10 |
| 452.47 | 2.15 | 2.15 |
| 470.46 | 2.08 | 2.08 |
| 494.48 | 2.08 | 2.08 |
| 490.52 | 2.17 | 2.17 |
| 586.63 | 2.69 | 2.69 |
| 495.47 | 1.33 | 1.33 |
| 510.48 | 1.24 | 1.24 |
| 498.56 | 2.22 | 2.22 |
| 482.49 | 1.28 | 1.28 |
| 462.46 | 1.61 | 1.61 |
| 478.51 | 2.47 | 2.47 |
| 496.52 | 1.93 | 1.93 |
| 496.52 | 1.67 | 1.67 |
| 484.48 | 2.26 | 2.26 |
| 533.54 | 1.25 | 1.25 |
| 498.49 | 0.46 | 0.46 |
| 484.48 | 2.44 | 2.44 |
| 456.43 | 2.03 | 2.03 |
| 494.50 | 1.66 | 1.66 |
| 482.49 | 1.49 | 1.49 |
| 468.47 | 1.10 | 1.10 |
| 513.48 | 0.91 | 0.91 |
| 499.50 | 1.38 | 1.38 |
| 514.51 | 1.81 | 1.81 |
| 500.48 | 1.44 | 1.44 |
| 494.50 | 1.87 | 1.87 |
| 495.47 | 1.95 | 1.95 |
| 510.55 | 2.32 | 2.32 |
| 491.50 | 1.50 | 1.50 |
| 545.39 | 2.68 | 2.68 |
| 500.94 | 2.96 | 2.96 |
| 480.52 | 2.61 | 2.61 |
| 467.48 | 1.50 | 1.50 |
| 502.47 | 2.39 | 2.39 |
| 481.51 | 1.89 | 1.89 |
| 492.49 | 1.62 | 1.62 |
| 544.49 | 2.94 | 2.94 |
| 511.49 | 2.21 | 2.21 |
| 521.49 | 1.83 | 1.83 |
| 466.49 | 2.22 | 2.22 |
| 490.52 | 2.23 | 2.23 |
| 514.51 | 1.81 | 1.81 |
| 496.50 | 2.61 | 2.61 |
| 500.48 | 1.42 | 1.42 |
| 506.52 | 1.93 | 1.93 |
| 484.48 | 2.44 | 2.44 |
| 502.47 | 2.39 | 2.39 |
| 496.50 | 2.61 | 2.61 |
| 496.52 | 2.31 | 2.31 |
| 500.48 | 1.42 | 1.42 |
| 456.43 | 2.03 | 2.03 |
| 510.93 | 2.57 | 2.57 |
| 494.48 | 2.06 | 2.06 |
| 477.48 | 1.19 | 1.19 |
| 458.50 | 1.98 | 1.98 |
| 482.52 | 1.98 | 1.98 |
| 472.52 | 2.37 | 2.37 |
| 486.55 | 2.76 | 2.76 |
| 484.53 | 2.53 | 2.53 |
| 490.51 | 2.32 | 2.32 |
| 488.52 | 1.34 | 1.34 |
| 502.55 | 1.73 | 1.73 |
| 483.51 | 1.87 | 1.87 |
| 483.51 | 1.38 | 1.38 |
| 445.46 | 1.35 | 1.35 |
| 459.48 | 1.37 | 1.37 |
| 473.51 | 1.76 | 1.76 |
| 485.52 | 1.93 | 1.93 |
| 491.50 | 1.71 | 1.71 |
| 489.51 | 0.73 | 0.73 |
| 503.54 | 1.12 | 1.12 |
| 473.51 | 1.76 | 1.76 |
| 474.50 | 1.16 | 1.16 |