Basic Information
ID: ALA1106892
Type: Binding
Description: Inhibition of SCD1 in human HepG2 cells assessed as [14C]stearic acid to [14C]oleic acid conversion pretreated 15 mins before [14C]stearic acid addition measured after 4 hrs by HPLC based scintillation assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Acyl-CoA desaturase(ALA5555)
Document: ALA1154928
Inhibition of SCD1 in human HepG2 cells assessed as [14C]stearic acid to [14C]oleic acid conversion pretreated 15 mins before [14C]stearic acid addition measured after 4 hrs by HPLC based scintillation assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1106892
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.38 | 2.22 | 2.22 |
| 420.44 | 1.77 | 1.77 |
| 370.40 | 2.58 | 2.58 |
| 387.45 | 4.02 | 4.02 |
| 371.38 | 3.31 | 3.31 |
| 357.36 | 2.92 | 2.92 |
| 357.36 | 2.92 | 2.92 |
| 371.38 | 3.31 | 3.31 |
| 372.37 | 2.70 | 2.70 |
| 356.30 | 2.24 | 2.24 |
| 356.30 | 2.24 | 2.24 |
| 355.32 | 1.97 | 1.97 |
| 355.32 | 2.84 | 2.84 |
| 407.44 | 2.86 | 2.86 |
| 411.45 | 4.34 | 4.34 |
| 386.40 | 3.70 | 3.70 |
| 401.41 | 4.39 | 4.39 |
| 426.49 | 5.04 | 5.04 |
| 395.41 | 4.86 | 4.86 |
| 396.39 | 4.26 | 4.26 |
| 396.39 | 4.26 | 4.26 |
| 410.42 | 4.57 | 4.57 |
| 426.42 | 3.75 | 3.75 |