Basic Information
ID: ALA1107066
Type: Functional
Description: Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assay relative to N-(4-(1H-1,2,4-triazol-1-yl)phenyl)-5-nitro-6-(4-(pyridin-2-ylthio)piperidin-1-yl)pyrimidin-4-amine maximal response
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Glucose-dependent insulinotropic receptor(ALA5652)
Document: ALA1156968
Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-transfected with 6CRE-Luc after 5 hrs by luciferase reporter gene assay relative to N-(4-(1H-1,2,4-triazol-1-yl)phenyl)-5-nitro-6-(4-(pyridin-2-ylthio)piperidin-1-yl)pyrimidin-4-amine maximal response: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1107066
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.55 | 2.52 | 2.52 |
| 461.61 | 2.36 | 2.36 |
| 404.51 | 2.39 | 2.39 |
| 456.54 | 3.27 | 3.27 |
| 420.55 | 2.49 | 2.49 |
| 454.59 | 2.19 | 2.19 |
| 468.62 | 2.58 | 2.58 |
| 468.62 | 2.58 | 2.58 |
| 482.65 | 2.97 | 2.97 |
| 484.62 | 1.82 | 1.82 |
| 508.69 | 3.50 | 3.50 |
| 522.71 | 3.75 | 3.75 |
| 503.63 | 2.62 | 2.62 |
| 508.67 | 3.29 | 3.29 |
| 497.66 | 2.43 | 2.43 |
| 509.67 | 2.57 | 2.57 |
| 467.64 | 2.15 | 2.15 |
| 466.65 | 2.61 | 2.61 |
| 481.66 | 2.54 | 2.54 |
| 480.68 | 3.00 | 3.00 |
| 507.70 | 3.08 | 3.08 |
| 460.55 | 1.83 | 1.83 |
| 476.60 | 2.47 | 2.47 |
| 495.65 | 1.49 | 1.49 |
| 543.73 | 4.39 | 4.39 |
| 440.57 | 1.94 | 1.94 |
| 468.62 | 2.58 | 2.58 |
| 482.65 | 2.97 | 2.97 |