Basic Information
ID: ALA1108118
Type: Functional
Description: Antagonist activity at human S1P1 receptor expressed in HEK293T cells assessed as inhibition of sphingosine-1-phosphate-induced gamma-[35S]GTP binding after 30 mins by scintillation counting
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: Sphingosine 1-phosphate receptor Edg-1(ALA4333)
Document: ALA1156167
Antagonist activity at human S1P1 receptor expressed in HEK293T cells assessed as inhibition of sphingosine-1-phosphate-induced gamma-[35S]GTP binding after 30 mins by scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1108118
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.48 | 4.04 | 4.04 |
| 470.46 | 3.74 | 3.74 |
| 479.47 | 4.61 | 4.61 |
| 482.47 | 3.93 | 3.93 |
| 538.46 | 4.76 | 4.76 |
| 561.50 | 5.67 | 5.67 |
| 547.47 | 5.62 | 5.62 |