Basic Information
ID: ALA1109146
Type: Binding
Description: Inhibition of Aurora A assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting
Format: BAO_0000357
Target: Serine/threonine-protein kinase Aurora-A(ALA4722)
Document: ALA1157785
Inhibition of Aurora A assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1109146
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.36 | 1.82 | 1.82 |
| 334.38 | 2.08 | 2.08 |
| 388.48 | 3.39 | 3.39 |
| 360.42 | 2.61 | 2.61 |
| 396.45 | 3.97 | 3.97 |
| 388.35 | 2.84 | 2.84 |
| 388.35 | 2.84 | 2.84 |
| 388.35 | 2.84 | 2.84 |
| 362.39 | 2.02 | 2.02 |
| 362.39 | 2.02 | 2.02 |
| 362.39 | 2.02 | 2.02 |
| 350.38 | 1.83 | 1.83 |
| 350.38 | 1.83 | 1.83 |
| 350.38 | 1.83 | 1.83 |
| 365.35 | 1.73 | 1.73 |
| 365.35 | 1.73 | 1.73 |
| 365.35 | 1.73 | 1.73 |
| 334.38 | 2.13 | 2.13 |
| 366.45 | 2.54 | 2.54 |
| 349.40 | 1.86 | 1.86 |
| 338.35 | 1.96 | 1.96 |
| 362.44 | 2.94 | 2.94 |
| 378.39 | 1.60 | 1.60 |
| 363.38 | 0.92 | 0.92 |
| 399.44 | 0.47 | 0.47 |
| 396.45 | 3.49 | 3.49 |
| 412.45 | 3.61 | 3.61 |
| 410.48 | 3.41 | 3.41 |
| 411.47 | 3.56 | 3.56 |
| 424.46 | 3.05 | 3.05 |
| 428.52 | 3.97 | 3.97 |
| 335.37 | 1.40 | 1.40 |
| 377.41 | 1.78 | 1.78 |
| 460.54 | 1.77 | 1.77 |
| 460.54 | 1.77 | 1.77 |
| 460.54 | 1.77 | 1.77 |
| 448.53 | 1.58 | 1.58 |
| 448.53 | 1.58 | 1.58 |
| 388.35 | 2.84 | 2.84 |
| 382.43 | 3.27 | 3.27 |
| 306.33 | 1.81 | 1.81 |
| 388.48 | 3.79 | 3.79 |
| 348.41 | 2.86 | 2.86 |
| 403.49 | 2.55 | 2.55 |
| 417.52 | 2.77 | 2.77 |
| 349.39 | 2.90 | 2.90 |
| 321.34 | 2.42 | 2.42 |