Basic Information
ID: ALA1109820
Type: Binding
Description: Ratio of IC50 of test compound to IC50 of NSC88915 for human Tdp1 assessed as blockade of enzyme-mediated hydrolysis of phosphodiester linkage between tyrosine and 3^-end of N14Y DNA substrate by SDS-PAGE electrophoresis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1109820
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.63 | 5.11 | 5.11 |
| 484.66 | 5.42 | 5.42 |
| 515.63 | 5.02 | 5.02 |
| 488.62 | 5.25 | 5.25 |
| 505.08 | 5.76 | 5.76 |