Basic Information
ID: ALA1110140
Type: Binding
Description: Binding affinity to human CFTR F508 deletion mutant expressed in FRT cells assessed as increase in iodine influx after 16 to 20 hrs by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: FRT
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA1158533
Binding affinity to human CFTR F508 deletion mutant expressed in FRT cells assessed as increase in iodine influx after 16 to 20 hrs by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1110140
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.99 | 5.97 | 5.97 |
| 463.03 | 6.15 | 6.15 |
| 426.54 | 4.52 | 4.52 |
| 568.50 | 6.31 | 6.31 |
| 453.57 | 4.75 | 4.75 |
| 437.57 | 4.42 | 4.42 |
| 487.63 | 5.28 | 5.28 |
| 568.10 | 6.27 | 6.27 |
| 532.07 | 4.48 | 4.48 |
| 506.03 | 3.73 | 3.73 |