Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular i...

Basic Information

ID: ALA1110793

Type: Functional

Description: Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular inositol phosphate accumulation at 100 uM after 1 hr by scintillation counting

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: HEK293

Target:  Metabotropic glutamate receptor 4(ALA2787)

Document:  ALA1156339

Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular inositol phosphate accumulation at 100 uM after 1 hr by scintillation counting: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
225.14-0.86-0.86
267.220.310.31
333.17-0.92-0.92
281.20-0.59-0.59