Basic Information
ID: ALA1110795
Type: Functional
Description: Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular inositol phosphate accumulation after 1 hr by scintillation counting
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HEK293
Target: Metabotropic glutamate receptor 6(ALA3842)
Document: ALA1156339
Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular inositol phosphate accumulation after 1 hr by scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1110795
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 183.10 | -1.03 | -1.03 |
| 217.18 | -1.04 | -1.04 |
| 239.16 | -0.47 | -0.47 |
| 239.16 | -0.47 | -0.47 |
| 239.16 | -0.47 | -0.47 |
| 225.14 | -0.86 | -0.86 |
| 253.19 | -0.08 | -0.08 |
| 283.17 | -1.01 | -1.01 |
| 297.20 | -0.77 | -0.77 |