Assay Report Card

Basic Information

ID: ALA1110798

Type: Functional

Description: Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
183.10-1.03-1.03
239.16-0.47-0.47
225.14-0.86-0.86
253.19-0.08-0.08
237.15-0.34-0.34
273.61-0.25-0.25
251.17-0.63-0.63
265.20-0.38-0.38
283.22-0.86-0.86
297.20-0.77-0.77
241.14-1.54-1.54
181.13-0.35-0.35
253.19-0.08-0.08