Assay Report Card

Basic Information

ID: ALA1110799

Type: Functional

Description: Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular inositol phosphate accumulation after 1 hr by scintillation counting

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
183.10-1.03-1.03
217.18-1.04-1.04
239.16-0.47-0.47
239.16-0.47-0.47
239.16-0.47-0.47
225.14-0.86-0.86
253.19-0.08-0.08
237.15-0.34-0.34
275.13-0.76-0.76
273.61-0.25-0.25
253.19-0.22-0.22
297.20-0.77-0.77
317.66-0.90-0.90