Basic Information
ID: ALA1111452
Type: Functional
Description: Inverse agonist activity at GABAA alpha-5-beta-3-gamma-2 receptor assessed as modulation of GABA-induced chloride ion flux by electrophysiology assay relative to GABA
Activity Charts
Bioactivity
Activity Types for Assay ALA1111452
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.36 | 3.21 | 3.21 |
| 316.16 | 2.56 | 2.56 |
| 330.19 | 2.87 | 2.87 |
| 372.27 | 3.86 | 3.86 |
| 360.22 | 2.71 | 2.71 |
| 370.25 | 3.52 | 3.52 |
| 413.28 | 2.69 | 2.69 |
| 411.26 | 3.45 | 3.45 |
| 412.25 | 2.85 | 2.85 |
| 366.81 | 3.34 | 3.34 |
| 416.36 | 3.59 | 3.59 |
| 332.37 | 2.69 | 2.69 |
| 346.39 | 3.00 | 3.00 |
| 362.39 | 2.70 | 2.70 |
| 348.37 | 2.39 | 2.39 |