Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-hydroxyquinoline to 7-benzyloxyquinoline at 10 uM measured every minute for ...

Basic Information

ID: ALA1111569

Type: ADME

Description: Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-hydroxyquinoline to 7-benzyloxyquinoline at 10 uM measured every minute for 15 mins by fluorescence intensity assay

Format: BAO_0000357

Organism: Homo sapiens

Target:  Cytochrome P450 3A4(ALA340)

Document:  ALA1156289

Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-hydroxyquinoline to 7-benzyloxyquinoline at 10 uM measured every minute for 15 mins by fluorescence intensity assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
496.67
484.66
509.68
583.80