Basic Information
ID: ALA1114101
Type: Functional
Description: Antagonist activity at estrogen receptor in human Ishikawa cells assessed as 17-beta-estradiol-induced alkaline phosphatase activity after 3 days by chemiluminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Ishikawa
Target: Estrogen receptor alpha(ALA206)
Document: ALA1153760
Antagonist activity at estrogen receptor in human Ishikawa cells assessed as 17-beta-estradiol-induced alkaline phosphatase activity after 3 days by chemiluminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1114101
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.59 | 6.08 | 6.08 |
| 371.52 | 6.00 | 6.00 |
| 429.52 | 5.16 | 5.16 |
| 457.57 | 5.94 | 5.94 |
| 457.57 | 5.94 | 5.94 |
| 483.61 | 6.47 | 6.47 |
| 483.61 | 6.47 | 6.47 |
| 469.58 | 6.08 | 6.08 |
| 469.58 | 6.08 | 6.08 |
| 475.56 | 6.08 | 6.08 |
| 475.56 | 6.08 | 6.08 |
| 501.60 | 6.61 | 6.61 |
| 501.60 | 6.61 | 6.61 |
| 429.52 | 5.16 | 5.16 |
| 429.52 | 5.16 | 5.16 |
| 483.61 | 6.47 | 6.47 |
| 469.58 | 6.08 | 6.08 |
| 469.58 | 6.08 | 6.08 |
| 499.61 | 6.09 | 6.09 |
| 499.61 | 6.09 | 6.09 |
| 499.61 | 6.09 | 6.09 |
| 499.61 | 6.09 | 6.09 |
| 513.63 | 6.40 | 6.40 |
| 513.63 | 6.40 | 6.40 |
| 503.62 | 5.35 | 5.35 |
| 483.61 | 6.47 | 6.47 |
| 485.58 | 5.79 | 5.79 |
| 499.61 | 6.18 | 6.18 |
| 485.58 | 5.79 | 5.79 |
| 485.58 | 5.79 | 5.79 |
| 445.52 | 4.87 | 4.87 |
| 445.52 | 4.87 | 4.87 |
| 501.62 | 6.42 | 6.42 |
| 501.62 | 6.42 | 6.42 |
| 499.61 | 6.18 | 6.18 |
| 499.61 | 6.18 | 6.18 |
| 471.55 | 5.40 | 5.40 |
| 471.55 | 5.40 | 5.40 |
| 487.55 | 4.64 | 4.64 |
| 487.55 | 4.64 | 4.64 |
| 503.62 | 5.35 | 5.35 |
| 503.62 | 5.35 | 5.35 |
| 500.60 | 4.55 | 4.55 |
| 500.60 | 4.55 | 4.55 |
| 499.52 | 4.45 | 4.45 |
| 499.52 | 4.45 | 4.45 |
| 513.55 | 4.84 | 4.84 |
| 513.55 | 4.84 | 4.84 |
| 418.45 | 4.30 | 4.30 |
| 432.47 | 4.69 | 4.69 |
| 446.46 | 4.48 | 4.48 |
| 446.46 | 4.78 | 4.78 |
| 446.46 | 4.78 | 4.78 |
| 499.61 | 6.18 | 6.18 |
| 499.61 | 6.18 | 6.18 |
| 485.58 | 5.79 | 5.79 |
| 485.58 | 5.79 | 5.79 |
| 500.60 | 4.55 | 4.55 |
| 500.60 | 4.55 | 4.55 |
| 503.62 | 5.35 | 5.35 |
| 429.52 | 5.16 | 5.16 |