Antagonist activity at estrogen receptor in human MCF7 cells assessed as 17-beta-estradiol-induced cell proliferation after 24 hrs by [14C]thymidine i...

Basic Information

ID: ALA1114102

Type: Functional

Description: Antagonist activity at estrogen receptor in human MCF7 cells assessed as 17-beta-estradiol-induced cell proliferation after 24 hrs by [14C]thymidine incorporation assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: MCF7

Target: Estrogen receptor alpha(ALA206)

Document: ALA1153760

Antagonist activity at estrogen receptor in human MCF7 cells assessed as 17-beta-estradiol-induced cell proliferation after 24 hrs by [14C]thymidine incorporation assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1114102

IC50

Total(61)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
473.59	6.08	6.08
371.52	6.00	6.00
429.52	5.16	5.16
457.57	5.94	5.94
457.57	5.94	5.94
483.61	6.47	6.47
483.61	6.47	6.47
469.58	6.08	6.08
469.58	6.08	6.08
475.56	6.08	6.08
475.56	6.08	6.08
501.60	6.61	6.61
501.60	6.61	6.61
429.52	5.16	5.16
429.52	5.16	5.16
483.61	6.47	6.47
469.58	6.08	6.08
469.58	6.08	6.08
499.61	6.09	6.09
499.61	6.09	6.09
499.61	6.09	6.09
499.61	6.09	6.09
513.63	6.40	6.40
513.63	6.40	6.40
503.62	5.35	5.35
483.61	6.47	6.47
485.58	5.79	5.79
499.61	6.18	6.18
485.58	5.79	5.79
485.58	5.79	5.79
445.52	4.87	4.87
445.52	4.87	4.87
501.62	6.42	6.42
501.62	6.42	6.42
499.61	6.18	6.18
499.61	6.18	6.18
471.55	5.40	5.40
471.55	5.40	5.40
487.55	4.64	4.64
487.55	4.64	4.64
503.62	5.35	5.35
503.62	5.35	5.35
500.60	4.55	4.55
500.60	4.55	4.55
499.52	4.45	4.45
499.52	4.45	4.45
513.55	4.84	4.84
513.55	4.84	4.84
418.45	4.30	4.30
432.47	4.69	4.69
446.46	4.48	4.48
446.46	4.78	4.78
446.46	4.78	4.78
499.61	6.18	6.18
499.61	6.18	6.18
485.58	5.79	5.79
485.58	5.79	5.79
500.60	4.55	4.55
500.60	4.55	4.55
503.62	5.35	5.35
429.52	5.16	5.16