Basic Information
ID: ALA1115116
Type: Functional
Description: Antiinflammatory activity in LPS-stimulated human THP1 cells assessed as inhibition of IL6 formation at 1 uM pretreated 30 mins before LPS challenge measured after 24 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: THP-1(ALA614245)
Document: ALA1156322
Antiinflammatory activity in LPS-stimulated human THP1 cells assessed as inhibition of IL6 formation at 1 uM pretreated 30 mins before LPS challenge measured after 24 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1115116
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.40 | 2.61 | 2.61 |
| 388.44 | 2.53 | 2.53 |
| 276.26 | 2.78 | 2.78 |
| 337.17 | 3.40 | 3.40 |
| 292.72 | 3.29 | 3.29 |
| 276.26 | 2.78 | 2.78 |
| 373.42 | 3.77 | 3.77 |
| 359.40 | 3.38 | 3.38 |
| 404.89 | 3.04 | 3.04 |
| 391.85 | 3.13 | 3.13 |
| 389.88 | 4.28 | 4.28 |
| 375.85 | 3.89 | 3.89 |
| 449.35 | 3.15 | 3.15 |
| 436.30 | 3.24 | 3.24 |
| 434.33 | 4.39 | 4.39 |
| 420.30 | 4.00 | 4.00 |
| 388.44 | 2.53 | 2.53 |
| 375.40 | 2.61 | 2.61 |
| 373.42 | 3.77 | 3.77 |
| 359.40 | 3.38 | 3.38 |