Basic Information
ID: ALA1115235
Type: Binding
Description: Inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis at 10 uM relative to control
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA1115235
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1297.30 | ||
| 696.68 | 8.15 | 8.15 |
| 504.50 | 3.54 | 3.54 |
| 458.43 | 0.26 | 0.26 |
| 477.50 | 3.88 | 3.88 |
| 362.32 | 1.61 | 1.61 |
| 550.57 | 4.44 | 4.44 |
| 578.62 | 5.06 | 5.06 |
| 541.56 | 3.42 | 3.42 |
| 486.44 | -0.81 | -0.81 |
| 452.47 | 0.68 | 0.68 |
| 509.58 | 0.95 | 0.95 |
| 578.62 | 5.06 | 5.06 |
| 486.48 | 0.86 | 0.86 |
| 637.55 | 2.39 | 2.39 |
| 675.75 | 8.55 | 8.55 |
| 357.37 | 2.29 | 2.29 |
| 288.32 | -0.73 | -0.73 |
| 527.54 | 4.71 | 4.71 |
| 900.89 | 8.63 | 8.63 |
| 608.58 | -0.14 | -0.14 |
| 442.50 | 1.01 | 1.01 |
| 632.63 | 2.62 | 2.62 |
| 514.49 | -0.20 | -0.20 |
| 652.57 | 3.64 | 3.64 |
| 727.78 | 5.27 | 5.27 |
| 535.52 | 2.74 | 2.74 |
| 504.50 | 3.54 | 3.54 |
| 870.87 | 5.13 | 5.13 |
| 426.43 | 0.85 | 0.85 |
| 491.50 | 2.27 | 2.27 |
| 454.44 | -0.22 | -0.22 |
| 572.54 | 5.36 | 5.36 |
| 577.60 | 6.61 | 6.61 |
| 846.90 | 6.52 | 6.52 |
| 372.36 | 3.25 | 3.25 |
| 487.47 | 1.19 | 1.19 |
| 416.39 | 1.73 | 1.73 |
| 904.89 | 6.07 | 6.07 |
| 887.89 | 8.36 | 8.36 |
| 764.78 | 6.81 | 6.81 |
| 856.87 | 9.08 | 9.08 |
| 778.83 | 8.99 | 8.99 |
| 888.85 | 4.58 | 4.58 |
| 852.89 | 9.52 | 9.52 |
| 755.79 | 8.53 | 8.53 |
| 980.94 | 4.70 | 4.70 |
| 776.78 | 6.36 | 6.36 |
| 856.87 | 9.08 | 9.08 |
| 901.91 | 8.67 | 8.67 |
| 760.83 | 8.01 | 8.01 |
| 876.87 | 8.16 | 8.16 |
| 870.90 | 9.39 | 9.39 |
| 551.67 | 6.60 | 6.60 |
| 870.90 | 9.39 | 9.39 |
| 913.88 | 9.13 | 9.13 |
| 842.85 | 8.77 | 8.77 |
| 836.84 | 7.94 | 7.94 |
| 913.88 | 9.13 | 9.13 |
| 693.78 | 5.76 | 5.76 |
| 872.85 | 3.86 | 3.86 |
| 793.81 | 8.04 | 8.04 |
| 837.89 | 8.88 | 8.88 |
| 1006.99 | ||
| 892.91 | 5.89 | 5.89 |
| 648.72 | 6.46 | 6.46 |
| 850.88 | 4.58 | 4.58 |
| 746.80 | 6.61 | 6.61 |
| 564.58 | 2.17 | 2.17 |
| 728.77 | 7.96 | 7.96 |
| 765.79 | 7.96 | 7.96 |
| 756.82 | 9.19 | 9.19 |
| 738.73 | 6.36 | 6.36 |
| 1005.07 | ||
| 699.73 | 7.64 | 7.64 |
| 742.75 | 7.54 | 7.54 |
| 489.49 | 3.90 | 3.90 |
| 714.71 | 5.06 | 5.06 |
| 870.87 | 5.13 | 5.13 |
| 562.60 | 7.13 | 7.13 |
| 659.75 | 8.85 | 8.85 |
| 1031.00 | ||
| 712.72 | 8.37 | 8.37 |
| 902.88 | 6.03 | 6.03 |
| 590.57 | 6.82 | 6.82 |
| 462.48 | 4.30 | 4.30 |
| 477.50 | 3.88 | 3.88 |
| 507.49 | 5.70 | 5.70 |
| 769.77 | 8.33 | 8.33 |
| 664.65 | 3.91 | 3.91 |
| 634.73 | 6.29 | 6.29 |
| 1225.20 | ||
| 422.40 | 1.31 | 1.31 |
| 388.36 | 2.95 | 2.95 |
| 640.66 | 3.49 | 3.49 |
| 461.47 | 3.64 | 3.64 |
| 578.62 | 5.06 | 5.06 |
| 512.53 | 0.70 | 0.70 |
| 662.79 | 7.13 | 7.13 |
| 1780.02 | ||
| 960.82 | 6.67 | 6.67 |
| 935.01 | 8.31 | 8.31 |
| 638.64 | 4.08 | 4.08 |