Basic Information
ID: ALA1115318
Type: Binding
Description: Activation of PKM2 assessed as ATP product formation at 57 uM by luminescent pyruvate kinase-luciferase coupled assay relative to fructose-1,6-bis-phosphate
Activity Charts
Bioactivity
Activity Types for Assay ALA1115318
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.54 | 0.92 | 0.92 |
| 426.52 | 1.40 | 1.40 |
| 449.51 | 1.02 | 1.02 |
| 458.95 | 1.81 | 1.81 |
| 442.49 | 1.29 | 1.29 |
| 442.49 | 1.29 | 1.29 |
| 442.49 | 1.29 | 1.29 |
| 460.48 | 1.43 | 1.43 |
| 454.53 | 1.16 | 1.16 |
| 490.51 | 1.44 | 1.44 |
| 502.56 | 2.38 | 2.38 |
| 476.48 | 1.14 | 1.14 |
| 460.48 | 1.43 | 1.43 |
| 424.50 | 1.15 | 1.15 |
| 492.50 | 2.17 | 2.17 |
| 454.53 | 1.16 | 1.16 |
| 425.49 | 0.55 | 0.55 |
| 441.49 | -0.21 | -0.21 |
| 459.49 | 2.36 | 2.36 |
| 424.43 | 1.88 | 1.88 |
| 432.47 | 1.67 | 1.67 |
| 438.42 | 1.94 | 1.94 |
| 474.51 | 1.82 | 1.82 |
| 446.45 | 1.39 | 1.39 |
| 473.52 | 1.49 | 1.49 |
| 452.50 | 2.81 | 2.81 |
| 486.56 | 2.76 | 2.76 |
| 455.51 | 2.15 | 2.15 |
| 473.55 | 2.58 | 2.58 |
| 459.49 | 2.36 | 2.36 |
| 424.43 | 1.88 | 1.88 |
| 474.51 | 1.82 | 1.82 |
| 434.44 | 0.99 | 0.99 |
| 448.47 | 1.38 | 1.38 |
| 462.50 | 1.77 | 1.77 |
| 476.52 | 2.16 | 2.16 |
| 490.55 | 2.55 | 2.55 |
| 488.53 | 2.30 | 2.30 |
| 488.53 | 2.30 | 2.30 |
| 474.51 | 1.87 | 1.87 |
| 474.51 | 1.87 | 1.87 |
| 460.48 | 1.48 | 1.48 |
| 460.48 | 1.48 | 1.48 |
| 460.48 | 1.33 | 1.33 |
| 460.48 | 1.34 | 1.34 |
| 474.51 | 1.82 | 1.82 |
| 474.51 | 1.82 | 1.82 |
| 474.51 | 1.82 | 1.82 |
| 474.51 | 1.82 | 1.82 |
| 474.46 | 0.96 | 0.96 |
| 474.46 | 0.96 | 0.96 |
| 447.49 | 1.25 | 1.25 |
| 439.52 | 0.74 | 0.74 |
| 417.46 | 1.24 | 1.24 |
| 461.51 | 1.64 | 1.64 |
| 453.54 | 1.13 | 1.13 |
| 478.47 | 1.57 | 1.57 |