Basic Information
ID: ALA1115329
Type: Functional
Description: Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HEK293
Target: Metabotropic glutamate receptor 4(ALA2787)
Document: ALA1156339
Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular calcium level after 1 hr by fluorescence microplate reader: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1115329
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 183.10 | -1.03 | -1.03 |
| 239.16 | -0.47 | -0.47 |
| 225.14 | -0.86 | -0.86 |
| 253.19 | -0.08 | -0.08 |
| 237.15 | -0.34 | -0.34 |
| 273.61 | -0.25 | -0.25 |
| 251.17 | -0.63 | -0.63 |
| 265.20 | -0.38 | -0.38 |
| 283.22 | -0.86 | -0.86 |
| 297.20 | -0.77 | -0.77 |
| 241.14 | -1.54 | -1.54 |
| 181.13 | -0.35 | -0.35 |
| 253.19 | -0.08 | -0.08 |