Basic Information
ID: ALA1116871
Type: Functional
Description: Antagonist activity at human histamine H4 receptor expressed in HEK293 cells coexpressing Galphaqi5 assessed as decrease in intracellular calcium by FLIPR
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Histamine H4 receptor(ALA3759)
Document: ALA1155405
Antagonist activity at human histamine H4 receptor expressed in HEK293 cells coexpressing Galphaqi5 assessed as decrease in intracellular calcium by FLIPR: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1116871
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.44 | 2.33 | 2.33 |
| 247.35 | 0.74 | 0.74 |
| 363.51 | 3.11 | 3.11 |
| 309.42 | 1.94 | 1.94 |
| 349.48 | 2.72 | 2.72 |
| 323.44 | 2.33 | 2.33 |
| 337.47 | 2.72 | 2.72 |
| 323.44 | 2.33 | 2.33 |
| 363.51 | 3.11 | 3.11 |
| 338.46 | 2.03 | 2.03 |
| 382.47 | 1.51 | 1.51 |
| 368.44 | 1.42 | 1.42 |
| 363.51 | 2.91 | 2.91 |
| 323.44 | 2.13 | 2.13 |
| 337.47 | 2.52 | 2.52 |
| 289.43 | 1.86 | 1.86 |
| 275.40 | 1.47 | 1.47 |
| 317.48 | 2.64 | 2.64 |
| 427.60 | 4.05 | 4.05 |
| 301.44 | 2.01 | 2.01 |
| 327.48 | 2.40 | 2.40 |
| 315.47 | 2.71 | 2.71 |
| 359.47 | 1.68 | 1.68 |
| 345.45 | 1.59 | 1.59 |
| 273.38 | 1.35 | 1.35 |
| 290.41 | 2.15 | 2.15 |
| 316.45 | 2.68 | 2.68 |
| 287.41 | 1.62 | 1.62 |
| 301.44 | 2.00 | 2.00 |
| 287.41 | 1.61 | 1.61 |
| 287.41 | 1.74 | 1.74 |
| 287.41 | 1.74 | 1.74 |
| 313.45 | 1.86 | 1.86 |
| 301.44 | 2.01 | 2.01 |
| 301.44 | 2.13 | 2.13 |
| 341.50 | 2.79 | 2.79 |
| 335.46 | 1.84 | 1.84 |
| 335.45 | 1.97 | 1.97 |