Basic Information
ID: ALA1117584
Type: Functional
Description: Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium flux relative to glutamate
Organism: Rattus norvegicus
Cell type: HEK293-A
Activity Charts
Bioactivity
Activity Types for Assay ALA1117584
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 343.34 | 3.13 | 3.13 |
| 360.34 | 3.88 | 3.88 |
| 360.34 | 3.88 | 3.88 |
| 306.32 | 2.38 | 2.38 |
| 360.41 | 3.41 | 3.41 |
| 342.83 | 4.72 | 4.72 |
| 328.80 | 4.33 | 4.33 |
| 314.77 | 3.94 | 3.94 |
| 316.79 | 4.19 | 4.19 |
| 288.73 | 3.55 | 3.55 |
| 318.76 | 3.18 | 3.18 |
| 358.35 | 3.45 | 3.45 |
| 402.41 | 3.76 | 3.76 |
| 372.38 | 3.75 | 3.75 |
| 376.80 | 4.39 | 4.39 |
| 343.34 | 3.13 | 3.13 |
| 380.83 | 4.85 | 4.85 |
| 380.83 | 4.85 | 4.85 |
| 380.83 | 4.85 | 4.85 |
| 415.28 | 5.51 | 5.51 |
| 415.28 | 5.51 | 5.51 |
| 364.38 | 4.34 | 4.34 |
| 364.38 | 4.34 | 4.34 |
| 414.38 | 5.22 | 5.22 |
| 371.40 | 4.07 | 4.07 |
| 360.41 | 4.51 | 4.51 |
| 390.40 | 3.93 | 3.93 |
| 336.35 | 3.79 | 3.79 |
| 360.41 | 4.13 | 4.13 |
| 386.45 | 4.69 | 4.69 |
| 404.51 | 5.10 | 5.10 |
| 352.43 | 4.47 | 4.47 |
| 338.41 | 4.08 | 4.08 |
| 324.38 | 3.69 | 3.69 |
| 310.35 | 3.30 | 3.30 |
| 312.37 | 3.54 | 3.54 |
| 284.32 | 2.91 | 2.91 |
| 314.34 | 2.53 | 2.53 |
| 385.25 | 5.50 | 5.50 |
| 385.25 | 5.50 | 5.50 |
| 385.25 | 5.50 | 5.50 |
| 419.70 | 6.15 | 6.15 |
| 368.80 | 4.98 | 4.98 |
| 368.80 | 4.98 | 4.98 |
| 418.80 | 5.86 | 5.86 |
| 364.83 | 5.15 | 5.15 |
| 394.81 | 4.57 | 4.57 |
| 340.77 | 4.44 | 4.44 |
| 364.83 | 4.77 | 4.77 |
| 390.87 | 5.33 | 5.33 |
| 408.93 | 5.75 | 5.75 |
| 356.85 | 5.11 | 5.11 |