Basic Information
ID: ALA1118158
Type: Binding
Description: Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: 11-beta-hydroxysteroid dehydrogenase 1(ALA4235)
Document: ALA1155502
Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1118158
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 233.30 | 1.95 | 1.95 |
| 275.38 | 2.97 | 2.97 |
| 295.37 | 3.24 | 3.24 |
| 313.36 | 3.38 | 3.38 |
| 313.36 | 3.38 | 3.38 |
| 325.39 | 3.25 | 3.25 |
| 325.39 | 3.25 | 3.25 |
| 355.42 | 3.26 | 3.26 |
| 309.39 | 3.17 | 3.17 |
| 285.33 | 2.84 | 2.84 |
| 301.40 | 3.30 | 3.30 |
| 293.35 | 1.81 | 1.81 |
| 321.40 | 2.85 | 2.85 |
| 335.43 | 3.03 | 3.03 |
| 369.45 | 3.57 | 3.57 |
| 369.45 | 3.57 | 3.57 |
| 369.45 | 3.57 | 3.57 |
| 383.47 | 3.88 | 3.88 |
| 385.45 | 3.27 | 3.27 |
| 389.86 | 3.91 | 3.91 |
| 369.45 | 3.32 | 3.32 |
| 375.48 | 3.38 | 3.38 |
| 291.38 | 1.99 | 1.99 |
| 307.38 | 1.66 | 1.66 |
| 279.30 | 2.53 | 2.53 |
| 292.34 | 2.59 | 2.59 |
| 277.33 | 3.08 | 3.08 |
| 291.35 | 3.14 | 3.14 |
| 292.34 | 2.79 | 2.79 |
| 291.35 | 3.39 | 3.39 |
| 291.35 | 3.39 | 3.39 |
| 311.77 | 3.74 | 3.74 |
| 311.77 | 3.74 | 3.74 |
| 307.35 | 3.09 | 3.09 |
| 307.35 | 3.09 | 3.09 |
| 307.35 | 3.09 | 3.09 |
| 302.34 | 2.95 | 2.95 |
| 279.30 | 1.87 | 1.87 |
| 318.38 | 3.02 | 3.02 |
| 331.42 | 4.02 | 4.02 |
| 242.28 | 1.82 | 1.82 |
| 269.35 | 3.21 | 3.21 |
| 283.38 | 3.60 | 3.60 |
| 285.35 | 2.45 | 2.45 |
| 292.34 | 2.41 | 2.41 |
| 306.37 | 2.80 | 2.80 |
| 295.32 | 3.22 | 3.22 |
| 296.31 | 2.62 | 2.62 |
| 311.77 | 3.74 | 3.74 |
| 311.77 | 3.74 | 3.74 |
| 307.35 | 3.09 | 3.09 |
| 257.34 | 2.82 | 2.82 |
| 284.36 | 2.74 | 2.74 |
| 278.31 | 2.61 | 2.61 |
| 308.34 | 2.62 | 2.62 |
| 308.34 | 2.62 | 2.62 |
| 322.32 | 2.34 | 2.34 |
| 311.77 | 3.74 | 3.74 |
| 312.76 | 3.27 | 3.27 |
| 312.76 | 3.27 | 3.27 |
| 279.30 | 2.01 | 2.01 |
| 280.29 | 1.40 | 1.40 |
| 280.29 | 1.40 | 1.40 |
| 283.36 | 3.14 | 3.14 |
| 361.47 | 3.78 | 3.78 |
| 335.45 | 4.02 | 4.02 |