Basic Information
ID: ALA1118523
Type: Toxicity
Description: Idiosyncratic toxicity in human liver microsomes assessed GSH-derived reactive electrophilic adduct formation at 10 uM after 60 mins by UPLC/HRMS analysis relative to labetalol
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Liver microsomes(ALA613373)
Document: ALA1155457
Idiosyncratic toxicity in human liver microsomes assessed GSH-derived reactive electrophilic adduct formation at 10 uM after 60 mins by UPLC/HRMS analysis relative to labetalol: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1118523
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.49 | 2.87 | 2.87 |
| 431.48 | 3.09 | 3.09 |
| 449.46 | 3.23 | 3.23 |
| 417.52 | 2.68 | 2.68 |
| 416.49 | 3.46 | 3.46 |
| 450.93 | 4.11 | 4.11 |