Basic Information
ID: ALA1118809
Type: Functional
Description: Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium level
Format: BAO_0000357
Organism: Rattus norvegicus
Target: Metabotropic glutamate receptor 5(ALA2564)
Document: ALA1158608
Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium level: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1118809
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 345.83 | 4.24 | 4.24 |
| 391.91 | 4.65 | 4.65 |
| 373.87 | 4.74 | 4.74 |
| 325.41 | 3.90 | 3.90 |
| 353.45 | 4.39 | 4.39 |
| 341.41 | 3.60 | 3.60 |
| 301.35 | 2.35 | 2.35 |
| 361.81 | 3.87 | 3.87 |
| 359.84 | 4.43 | 4.43 |
| 364.43 | 4.04 | 4.04 |
| 436.70 | 4.04 | 4.04 |
| 325.42 | 2.82 | 2.82 |
| 345.83 | 3.17 | 3.17 |
| 359.86 | 3.56 | 3.56 |
| 373.87 | 3.66 | 3.66 |