Basic Information
ID: ALA1119709
Type: Binding
Description: Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillation counting
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA1119709
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.83 | 3.72 | 3.72 |
| 339.39 | 3.86 | 3.86 |
| 392.46 | 5.28 | 5.28 |
| 343.39 | 3.12 | 3.12 |
| 387.40 | 2.89 | 2.89 |
| 343.39 | 2.75 | 2.75 |
| 314.35 | 2.04 | 2.04 |
| 328.38 | 2.30 | 2.30 |
| 356.43 | 3.08 | 3.08 |
| 335.39 | 1.53 | 1.53 |
| 349.42 | 1.92 | 1.92 |
| 363.44 | 2.31 | 2.31 |
| 377.47 | 2.70 | 2.70 |
| 377.47 | 2.70 | 2.70 |
| 244.25 | 1.60 | 1.60 |
| 258.28 | 1.91 | 1.91 |
| 272.31 | 2.17 | 2.17 |
| 272.31 | 2.25 | 2.25 |
| 286.34 | 2.56 | 2.56 |
| 300.36 | 2.95 | 2.95 |
| 300.36 | 2.94 | 2.94 |
| 403.39 | 2.81 | 2.81 |
| 363.44 | 1.94 | 1.94 |
| 256.31 | 2.55 | 2.55 |
| 242.28 | 2.21 | 2.21 |
| 256.31 | 2.47 | 2.47 |
| 270.34 | 2.86 | 2.86 |
| 256.31 | 2.55 | 2.55 |
| 240.31 | 2.85 | 2.85 |
| 254.34 | 3.16 | 3.16 |
| 306.32 | 3.45 | 3.45 |
| 298.39 | 3.64 | 3.64 |
| 312.42 | 4.03 | 4.03 |
| 310.40 | 3.95 | 3.95 |
| 284.36 | 3.10 | 3.10 |
| 318.38 | 3.49 | 3.49 |
| 332.41 | 3.69 | 3.69 |
| 306.32 | 3.48 | 3.48 |
| 324.31 | 3.57 | 3.57 |
| 284.36 | 3.11 | 3.11 |
| 314.35 | 2.33 | 2.33 |
| 328.37 | 2.72 | 2.72 |
| 427.51 | 1.27 | 1.27 |
| 314.39 | 3.33 | 3.33 |
| 376.46 | 4.17 | 4.17 |
| 390.49 | 4.56 | 4.56 |
| 274.35 | 2.62 | 2.62 |
| 288.38 | 2.88 | 2.88 |
| 302.40 | 3.27 | 3.27 |
| 304.38 | 1.89 | 1.89 |
| 318.40 | 2.28 | 2.28 |
| 334.40 | 1.95 | 1.95 |
| 271.32 | 2.20 | 2.20 |
| 285.35 | 2.59 | 2.59 |
| 299.38 | 2.61 | 2.61 |
| 281.32 | 2.42 | 2.42 |
| 267.29 | 2.03 | 2.03 |
| 321.38 | 3.51 | 3.51 |
| 299.33 | 2.12 | 2.12 |
| 313.36 | 2.51 | 2.51 |
| 327.39 | 2.90 | 2.90 |
| 329.36 | 2.73 | 2.73 |