Basic Information
ID: ALA1119825
Type: Functional
Description: Antagonist activity at human OX1R expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium mobilization after 5 mins by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Orexin receptor 1(ALA5113)
Document: ALA1155457
Antagonist activity at human OX1R expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium mobilization after 5 mins by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1119825
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.49 | 2.87 | 2.87 |
| 427.51 | 3.26 | 3.26 |
| 413.49 | 2.95 | 2.95 |
| 431.48 | 3.09 | 3.09 |
| 449.46 | 3.23 | 3.23 |
| 417.52 | 2.68 | 2.68 |
| 416.49 | 3.46 | 3.46 |
| 450.93 | 4.11 | 4.11 |