Basic Information
ID: ALA1120300
Type: Binding
Description: Maximum activation of human PKM2 assessed as ATP product formation at 57 uM after 1 hr by luminescent pyruvate kinase-luciferase coupled assay relative to fructose-1,6-bis-phosphate
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1120300
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.38 | 3.45 | 3.45 |
| 341.41 | 3.70 | 3.70 |
| 355.44 | 4.26 | 4.26 |
| 313.36 | 3.14 | 3.14 |
| 343.38 | 3.15 | 3.15 |
| 359.45 | 3.86 | 3.86 |
| 375.45 | 2.87 | 2.87 |
| 391.45 | 2.54 | 2.54 |
| 358.35 | 3.05 | 3.05 |
| 370.41 | 3.10 | 3.10 |
| 338.37 | 3.01 | 3.01 |
| 371.39 | 2.92 | 2.92 |
| 341.37 | 2.95 | 2.95 |
| 343.38 | 2.63 | 2.63 |
| 357.18 | ||
| 355.39 | 3.34 | 3.34 |
| 357.41 | 3.19 | 3.19 |
| 313.36 | 3.44 | 3.44 |
| 341.41 | 3.93 | 3.93 |
| 355.44 | 4.49 | 4.49 |
| 341.41 | 3.75 | 3.75 |
| 313.36 | 3.14 | 3.14 |
| 295.37 | 3.25 | 3.25 |
| 289.40 | 3.45 | 3.45 |
| 309.39 | 3.31 | 3.31 |
| 327.38 | 3.45 | 3.45 |
| 327.38 | 3.45 | 3.45 |
| 343.84 | 3.96 | 3.96 |
| 343.84 | 3.96 | 3.96 |
| 343.84 | 3.96 | 3.96 |
| 323.42 | 3.61 | 3.61 |
| 377.39 | 4.33 | 4.33 |
| 339.42 | 3.32 | 3.32 |
| 345.37 | 3.58 | 3.58 |
| 345.37 | 3.58 | 3.58 |
| 345.37 | 3.58 | 3.58 |
| 361.83 | 4.10 | 4.10 |
| 363.36 | 3.72 | 3.72 |
| 381.35 | 3.86 | 3.86 |
| 341.41 | 3.75 | 3.75 |
| 341.41 | 3.75 | 3.75 |
| 395.38 | 4.46 | 4.46 |
| 357.41 | 3.45 | 3.45 |
| 387.49 | 2.74 | 2.74 |
| 372.48 | 2.32 | 2.32 |
| 373.46 | 2.44 | 2.44 |