Basic Information
ID: ALA1120487
Type: Binding
Description: Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB expression by luciferase reporter gene assay
Format: BAO_0000219
Cell type: HeLa
Target: Inhibitor of nuclear factor kappa B kinase beta subunit(ALA1991)
Document: ALA1155535
Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB expression by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1120487
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.44 | 2.90 | 2.90 |
| 326.38 | 2.53 | 2.53 |
| 352.42 | 2.63 | 2.63 |
| 366.45 | 3.02 | 3.02 |
| 356.41 | 2.54 | 2.54 |
| 382.45 | 2.64 | 2.64 |
| 439.54 | 3.91 | 3.91 |
| 465.58 | 4.01 | 4.01 |
| 459.53 | 3.72 | 3.72 |
| 485.57 | 3.81 | 3.81 |
| 465.56 | 3.78 | 3.78 |
| 491.60 | 3.88 | 3.88 |
| 491.60 | 3.88 | 3.88 |
| 515.60 | 3.82 | 3.82 |
| 451.55 | 3.62 | 3.62 |
| 449.54 | 3.54 | 3.54 |
| 463.56 | 3.76 | 3.76 |
| 437.53 | 3.23 | 3.23 |
| 467.51 | 2.13 | 2.13 |
| 461.50 | 3.48 | 3.48 |
| 332.41 | 2.60 | 2.60 |
| 358.45 | 2.69 | 2.69 |
| 403.53 | 2.79 | 2.79 |
| 429.57 | 2.89 | 2.89 |
| 417.56 | 3.18 | 3.18 |
| 443.60 | 3.28 | 3.28 |
| 376.46 | 2.22 | 2.22 |
| 402.50 | 2.32 | 2.32 |