Assay Report Card

Basic Information

ID: ALA1120542

Type: Functional

Description: Agonist activity at human TLR8 expressed in NF-kappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by reporter gene assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
240.312.822.82
313.402.052.05
341.462.782.78
355.442.312.31
551.827.777.77
468.652.682.68
444.581.751.75
366.472.672.67
370.502.112.11
614.912.312.31
439.655.565.56
288.353.523.52
302.383.783.78
316.414.174.17
330.444.564.56
344.464.954.95
358.495.345.34
372.525.735.73
400.576.516.51
428.627.297.29
484.738.858.85
328.424.334.33
326.403.783.78
363.896.026.02
345.455.075.07
405.557.037.03
346.434.784.78
345.454.264.26
315.424.984.98
331.423.323.32
312.423.283.28
294.743.683.68
275.312.612.61
360.423.373.37