Basic Information
ID: ALA1120648
Type: Binding
Description: Inhibition of gamma-secretase-mediated cleavage of human APP Swedish and London mutation expressed in HEK293 cell membrane
Format: BAO_0000219
Cell type: HEK293
Target: Unchecked(ALA612545)
Document: ALA1158621
Inhibition of gamma-secretase-mediated cleavage of human APP Swedish and London mutation expressed in HEK293 cell membrane: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1120648
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.03 | 3.49 | 3.49 |
| 506.98 | 2.89 | 2.89 |
| 546.06 | 4.57 | 4.57 |
| 532.03 | 4.18 | 4.18 |
| 534.05 | 4.42 | 4.42 |
| 592.08 | 3.97 | 3.97 |
| 548.07 | 4.82 | 4.82 |
| 534.05 | 4.43 | 4.43 |
| 573.99 | 4.58 | 4.58 |
| 520.02 | 4.04 | 4.04 |
| 559.96 | 4.54 | 4.54 |
| 539.54 | 4.01 | 4.01 |
| 553.57 | 4.40 | 4.40 |
| 593.51 | 4.90 | 4.90 |
| 607.54 | 4.94 | 4.94 |
| 565.58 | 4.54 | 4.54 |
| 540.53 | 3.25 | 3.25 |
| 568.59 | 3.86 | 3.86 |
| 505.99 | 3.65 | 3.65 |
| 563.09 | 4.27 | 4.27 |
| 561.07 | 4.03 | 4.03 |
| 575.10 | 4.42 | 4.42 |
| 577.07 | 3.26 | 3.26 |
| 568.06 | 5.07 | 5.07 |
| 574.09 | 5.14 | 5.14 |
| 604.04 | 5.35 | 5.35 |
| 567.60 | 4.74 | 4.74 |
| 621.57 | 5.63 | 5.63 |
| 593.64 | 5.28 | 5.28 |
| 579.61 | 4.89 | 4.89 |
| 593.64 | 5.28 | 5.28 |
| 633.58 | 5.78 | 5.78 |
| 565.58 | 4.50 | 4.50 |
| 579.61 | 4.89 | 4.89 |
| 566.57 | 3.61 | 3.61 |
| 580.60 | 3.95 | 3.95 |
| 534.05 | 4.38 | 4.38 |
| 548.07 | 4.77 | 4.77 |
| 560.08 | 4.91 | 4.91 |
| 546.06 | 4.52 | 4.52 |
| 600.03 | 5.41 | 5.41 |