Basic Information
ID: ALA1120985
Type: Functional
Description: Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor activation by luciferase reporter gene assay
Format: BAO_0000219
Cell type: Huh-7
Target: Mineralocorticoid receptor(ALA1994)
Document: ALA1157753
Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor activation by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1120985
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.45 | 4.34 | 4.34 |
| 361.45 | 4.34 | 4.34 |
| 353.81 | 3.39 | 3.39 |
| 353.81 | 3.39 | 3.39 |
| 355.20 | 3.63 | 3.63 |
| 355.20 | 3.63 | 3.63 |
| 414.50 | 3.12 | 3.12 |
| 388.42 | 3.34 | 3.34 |
| 388.42 | 3.34 | 3.34 |
| 388.42 | 3.34 | 3.34 |
| 362.83 | 4.58 | 4.58 |
| 362.83 | 4.58 | 4.58 |
| 362.83 | 4.58 | 4.58 |
| 319.36 | 3.17 | 3.17 |
| 319.36 | 3.17 | 3.17 |
| 361.45 | 4.34 | 4.34 |