Basic Information
ID: ALA1121077
Type: Functional
Description: Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 200 nM by FLIPR calcium 4 assay
Format: BAO_0000219
Organism: Oryctolagus cuniculus
Cell type: HEK293
Target: Voltage-gated L-type calcium channel alpha-1C subunit(ALA2830)
Document: ALA1158565
Antagonist activity at rabbit Cav1.2 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current at 200 nM by FLIPR calcium 4 assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1121077
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.38 | 3.28 | 3.28 |
| 359.42 | 3.90 | 3.90 |
| 330.38 | 3.28 | 3.28 |
| 335.43 | 3.95 | 3.95 |
| 388.42 | 3.34 | 3.34 |
| 374.39 | 2.95 | 2.95 |
| 388.42 | 3.20 | 3.20 |
| 455.29 | 3.65 | 3.65 |
| 397.39 | 4.07 | 4.07 |
| 408.84 | 3.61 | 3.61 |
| 408.84 | 3.61 | 3.61 |
| 487.19 | 4.57 | 4.57 |
| 465.39 | 5.09 | 5.09 |
| 405.49 | 4.71 | 4.71 |
| 319.36 | 2.64 | 2.64 |
| 335.42 | 3.11 | 3.11 |
| 364.35 | 2.55 | 2.55 |
| 379.46 | 4.20 | 4.20 |
| 385.49 | 4.26 | 4.26 |
| 295.38 | 2.68 | 2.68 |
| 335.44 | 3.46 | 3.46 |
| 402.45 | 3.73 | 3.73 |
| 430.50 | 4.23 | 4.23 |
| 388.42 | 3.35 | 3.35 |
| 482.33 | 4.04 | 4.04 |
| 505.33 | 5.15 | 5.15 |
| 319.36 | 3.48 | 3.48 |