Basic Information
ID: ALA1121084
Type: Functional
Description: Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1121084
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.37 | 3.28 | 3.28 |
| 402.45 | 3.74 | 3.74 |
| 416.47 | 4.13 | 4.13 |
| 390.39 | 2.19 | 2.19 |
| 390.39 | 2.19 | 2.19 |
| 376.37 | 1.80 | 1.80 |
| 390.39 | 1.93 | 1.93 |
| 408.84 | 3.17 | 3.17 |
| 432.43 | 2.50 | 2.50 |
| 494.50 | 3.79 | 3.79 |
| 462.50 | 3.34 | 3.34 |
| 534.61 | 3.76 | 3.76 |
| 411.41 | 3.02 | 3.02 |
| 444.44 | 2.67 | 2.67 |
| 507.50 | 4.56 | 4.56 |
| 482.49 | 3.76 | 3.76 |
| 452.46 | 3.75 | 3.75 |
| 525.77 | 5.71 | 5.71 |
| 458.42 | 4.02 | 4.02 |
| 440.43 | 3.89 | 3.89 |
| 512.43 | 3.56 | 3.56 |
| 481.46 | 4.04 | 4.04 |
| 412.44 | 3.65 | 3.65 |
| 374.35 | 2.09 | 2.09 |
| 422.44 | 3.75 | 3.75 |
| 471.39 | 2.22 | 2.22 |
| 458.47 | 3.06 | 3.06 |
| 416.47 | 4.13 | 4.13 |
| 419.39 | 2.21 | 2.21 |
| 385.38 | 2.46 | 2.46 |
| 414.34 | 3.11 | 3.11 |
| 394.81 | 2.78 | 2.78 |
| 404.42 | 2.58 | 2.58 |
| 386.40 | 2.96 | 2.96 |
| 400.43 | 3.51 | 3.51 |
| 384.39 | 2.57 | 2.57 |
| 386.40 | 3.12 | 3.12 |
| 372.38 | 2.73 | 2.73 |
| 372.38 | 2.73 | 2.73 |
| 332.31 | 2.09 | 2.09 |
| 466.45 | 3.47 | 3.47 |
| 412.40 | 3.34 | 3.34 |
| 428.47 | 3.81 | 3.81 |
| 448.48 | 3.71 | 3.71 |
| 470.91 | 4.44 | 4.44 |
| 448.48 | 4.26 | 4.26 |
| 486.91 | 4.28 | 4.28 |
| 464.52 | 4.57 | 4.57 |
| 464.52 | 4.74 | 4.74 |
| 494.54 | 4.58 | 4.58 |
| 466.49 | 3.76 | 3.76 |
| 466.49 | 4.01 | 4.01 |
| 498.54 | 5.41 | 5.41 |
| 526.59 | 5.77 | 5.77 |
| 508.62 | 5.54 | 5.54 |
| 365.38 | 3.33 | 3.33 |
| 365.38 | 3.33 | 3.33 |
| 271.27 | 3.25 | 3.25 |
| 347.44 | 2.99 | 2.99 |
| 375.49 | 3.77 | 3.77 |
| 343.42 | 3.22 | 3.22 |
| 344.32 | 1.93 | 1.93 |
| 375.38 | 3.38 | 3.38 |
| 391.47 | 4.37 | 4.37 |
| 349.43 | 4.23 | 4.23 |
| 385.38 | 2.46 | 2.46 |
| 385.38 | 2.46 | 2.46 |
| 399.40 | 2.85 | 2.85 |
| 399.40 | 2.85 | 2.85 |