Basic Information
ID: ALA1121265
Type: Functional
Description: Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium flux by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Metabotropic glutamate receptor 2(ALA5137)
Document: ALA1157756
Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium flux by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1121265
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 262.35 | 3.56 | 3.56 |
| 262.35 | 3.56 | 3.56 |
| 262.35 | 3.56 | 3.56 |
| 305.37 | 3.77 | 3.77 |
| 305.37 | 3.77 | 3.77 |
| 325.43 | 3.39 | 3.39 |
| 325.43 | 3.39 | 3.39 |
| 261.37 | 4.29 | 4.29 |
| 261.37 | 4.29 | 4.29 |
| 261.37 | 4.29 | 4.29 |
| 265.33 | 4.12 | 4.12 |
| 265.33 | 4.12 | 4.12 |
| 265.33 | 4.12 | 4.12 |
| 281.78 | 4.64 | 4.64 |
| 281.78 | 4.64 | 4.64 |
| 281.78 | 4.64 | 4.64 |
| 272.35 | 3.85 | 3.85 |
| 272.35 | 3.85 | 3.85 |
| 272.35 | 3.85 | 3.85 |
| 277.36 | 3.99 | 3.99 |
| 277.36 | 3.99 | 3.99 |
| 277.36 | 3.99 | 3.99 |
| 263.34 | 3.69 | 3.69 |
| 263.34 | 3.69 | 3.69 |
| 263.34 | 3.69 | 3.69 |
| 305.37 | 3.77 | 3.77 |
| 325.43 | 3.39 | 3.39 |
| 247.34 | 3.98 | 3.98 |
| 275.39 | 4.76 | 4.76 |
| 233.31 | 3.59 | 3.59 |
| 219.28 | 3.20 | 3.20 |
| 253.30 | 3.25 | 3.25 |
| 269.30 | 3.09 | 3.09 |
| 303.75 | 3.74 | 3.74 |
| 283.33 | 3.40 | 3.40 |
| 283.33 | 3.40 | 3.40 |
| 283.33 | 3.40 | 3.40 |
| 297.35 | 3.65 | 3.65 |
| 297.35 | 3.65 | 3.65 |
| 297.35 | 3.65 | 3.65 |
| 311.38 | 4.21 | 4.21 |
| 311.38 | 4.21 | 4.21 |
| 311.38 | 4.21 | 4.21 |
| 325.41 | 4.39 | 4.39 |
| 325.41 | 4.39 | 4.39 |
| 299.33 | 3.10 | 3.10 |
| 299.33 | 3.10 | 3.10 |
| 299.33 | 3.10 | 3.10 |
| 303.75 | 3.74 | 3.74 |
| 303.75 | 3.74 | 3.74 |
| 337.30 | 4.11 | 4.11 |
| 337.30 | 4.11 | 4.11 |
| 337.30 | 4.11 | 4.11 |
| 284.32 | 2.67 | 2.67 |
| 284.32 | 2.67 | 2.67 |
| 312.33 | 2.19 | 2.19 |
| 312.33 | 2.19 | 2.19 |
| 326.35 | 3.05 | 3.05 |
| 326.35 | 3.05 | 3.05 |
| 326.35 | 3.05 | 3.05 |
| 247.34 | 3.98 | 3.98 |
| 350.42 | 4.26 | 4.26 |
| 350.42 | 4.26 | 4.26 |