Basic Information
ID: ALA1166118
Type: Binding
Description: Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly PCDH15 R245X nonsense mutant gene transfected in rabbit reticulocyte assessed as reduction in overall translation at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay
Format: BAO_0000220
Organism: Oryctolagus cuniculus
Subcellular Fraction: Ribosome
Target: Ribosome(ALA613299)
Document: ALA1165913
Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly PCDH15 R245X nonsense mutant gene transfected in rabbit reticulocyte assessed as reduction in overall translation at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1166118
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.48 | -6.65 | -6.65 |
| 555.58 | -7.79 | -7.79 |
| 468.50 | -6.26 | -6.26 |
| 569.61 | -7.40 | -7.40 |