Basic Information
ID: ALA1166125
Type: Binding
Description: Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly CFTR W1282X nonsense mutant gene transfected in HEK293 cells assessed as reduction in overall translation at 1 to 2 mM after 6 hrs dual-luciferase reporter gene assay
Format: BAO_0000220
Organism: Homo sapiens
Cell type: HEK293
Subcellular Fraction: Ribosome
Target: Ribosome(ALA613299)
Document: ALA1165913
Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly CFTR W1282X nonsense mutant gene transfected in HEK293 cells assessed as reduction in overall translation at 1 to 2 mM after 6 hrs dual-luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1166125
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 555.58 | -7.79 | -7.79 |
| 569.61 | -7.40 | -7.40 |