Basic Information
ID: ALA1169087
Type: Binding
Description: Inhibition of BACE1 after 2 hrs by FRET assay
Activity Charts
Bioactivity
Activity Types for Assay ALA1169087
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 510.43 | 5.91 | 5.91 |
| 500.44 | 6.18 | 6.18 |
| 528.40 | 4.86 | 4.86 |
| 518.41 | 5.13 | 5.13 |
| 558.43 | 4.87 | 4.87 |
| 548.44 | 5.14 | 5.14 |
| 596.73 | 3.17 | 3.17 |
| 502.37 | 2.93 | 2.93 |
| 515.61 | 6.03 | 6.03 |
| 511.63 | 6.72 | 6.72 |
| 578.74 | 3.03 | 3.03 |
| 622.77 | 7.35 | 7.35 |
| 541.70 | 7.00 | 7.00 |
| 541.70 | 7.00 | 7.00 |
| 595.83 | 7.77 | 7.77 |
| 472.34 | 2.92 | 2.92 |
| 459.30 | 3.65 | 3.65 |
| 493.61 | 5.44 | 5.44 |
| 410.32 | 4.26 | 4.26 |
| 492.67 | 6.01 | 6.01 |
| 454.37 | 3.97 | 3.97 |
| 497.64 | 7.08 | 7.08 |
| 407.52 | 5.17 | 5.17 |
| 411.30 | 4.69 | 4.69 |
| 451.57 | 4.87 | 4.87 |
| 429.27 | 3.64 | 3.64 |
| 495.52 | 3.66 | 3.66 |
| 612.77 | 3.80 | 3.80 |
| 606.79 | 3.81 | 3.81 |
| 607.78 | 2.87 | 2.87 |
| 553.68 | 3.71 | 3.71 |
| 484.60 | 4.34 | 4.34 |
| 571.67 | 3.85 | 3.85 |
| 556.66 | 2.37 | 2.37 |
| 584.71 | 3.02 | 3.02 |
| 490.63 | 2.90 | 2.90 |
| 450.58 | 5.75 | 5.75 |
| 486.04 | 3.13 | 3.13 |
| 541.07 | 4.19 | 4.19 |
| 540.45 | 5.90 | 5.90 |
| 458.35 | 4.07 | 4.07 |
| 591.31 | 5.05 | 5.05 |
| 474.73 | 2.49 | 2.49 |
| 482.01 | 4.86 | 4.86 |
| 484.58 | 1.72 | 1.72 |
| 474.91 | 5.08 | 5.08 |
| 560.58 | 6.82 | 6.82 |
| 633.93 | 8.94 | 8.94 |
| 425.49 | 3.28 | 3.28 |
| 499.36 | 2.37 | 2.37 |
| 456.29 | 1.97 | 1.97 |
| 450.33 | 6.11 | 6.11 |
| 468.36 | 3.97 | 3.97 |
| 492.80 | 5.17 | 5.17 |
| 381.47 | 3.93 | 3.93 |
| 376.37 | 0.44 | 0.44 |
| 358.39 | 2.21 | 2.21 |
| 609.76 | 4.94 | 4.94 |
| 365.39 | 0.25 | 0.25 |
| 488.78 | 4.31 | 4.31 |
| 657.25 | 3.68 | 3.68 |
| 460.92 | 5.39 | 5.39 |
| 517.52 | 4.85 | 4.85 |
| 536.59 | 3.71 | 3.71 |
| 485.33 | 4.39 | 4.39 |
| 384.21 | 3.18 | 3.18 |
| 647.73 | 3.57 | 3.57 |
| 454.26 | 3.23 | 3.23 |
| 290.28 | -1.47 | -1.47 |
| 517.98 | 5.66 | 5.66 |
| 537.94 | 4.65 | 4.65 |
| 483.53 | 5.01 | 5.01 |
| 402.28 | 3.52 | 3.52 |
| 397.86 | 2.87 | 2.87 |
| 403.44 | 0.24 | 0.24 |
| 478.59 | 3.53 | 3.53 |
| 381.86 | 3.17 | 3.17 |
| 445.31 | 2.62 | 2.62 |
| 553.68 | 3.71 | 3.71 |
| 440.89 | 1.97 | 1.97 |
| 410.86 | 1.96 | 1.96 |
| 582.70 | 3.14 | 3.14 |
| 647.15 | 4.63 | 4.63 |
| 626.74 | 4.28 | 4.28 |
| 647.15 | 4.63 | 4.63 |
| 612.71 | 3.97 | 3.97 |
| 630.70 | 4.11 | 4.11 |
| 529.04 | 4.15 | 4.15 |
| 549.46 | 4.49 | 4.49 |
| 362.34 | 0.95 | 0.95 |
| 405.41 | 0.68 | 0.68 |
| 390.39 | 0.75 | 0.75 |
| 405.41 | 0.68 | 0.68 |
| 391.38 | 0.37 | 0.37 |
| 529.04 | 4.15 | 4.15 |
| 457.00 | 3.97 | 3.97 |
| 474.56 | 3.72 | 3.72 |
| 480.36 | 4.53 | 4.53 |
| 604.23 | 2.87 | 2.87 |
| 498.44 | 6.01 | 6.01 |
| 468.54 | 1.41 | 1.41 |
| 501.45 | 4.08 | 4.08 |
| 535.07 | 4.57 | 4.57 |
| 428.29 | 3.22 | 3.22 |
| 495.71 | 6.37 | 6.37 |
| 460.60 | 2.31 | 2.31 |
| 460.58 | 1.80 | 1.80 |
| 458.31 | 3.23 | 3.23 |
| 460.60 | 2.16 | 2.16 |
| 463.36 | 6.17 | 6.17 |
| 487.58 | 3.25 | 3.25 |
| 462.57 | 1.15 | 1.15 |
| 425.49 | 4.12 | 4.12 |
| 672.75 | 5.24 | 5.24 |
| 500.36 | 3.37 | 3.37 |
| 479.63 | 5.88 | 5.88 |
| 477.91 | 3.12 | 3.12 |
| 455.03 | 5.52 | 5.52 |
| 458.36 | 2.21 | 2.21 |
| 466.33 | 5.82 | 5.82 |
| 577.28 | 4.43 | 4.43 |
| 595.18 | 2.13 | 2.13 |
| 693.29 | 4.97 | 4.97 |
| 454.55 | 1.57 | 1.57 |
| 543.51 | 4.69 | 4.69 |
| 459.50 | 2.99 | 2.99 |
| 466.99 | 6.17 | 6.17 |
| 649.23 | 5.72 | 5.72 |
| 555.23 | 6.04 | 6.04 |
| 577.28 | 4.75 | 4.75 |
| 597.70 | 5.09 | 5.09 |
| 479.92 | 4.78 | 4.78 |
| 477.57 | 3.58 | 3.58 |
| 510.68 | 7.05 | 7.05 |
| 479.51 | 2.62 | 2.62 |