ID: ALA1176286
Type: Functional
Description: Antagonist activity at alpha3beta4 nicotinic receptor in human SH-SY5Y cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx at by liquid scintillation counting
Organism: Homo sapiens
Cell type: SH-SY5Y
Bioactivity
Activity Types for Assay ALA1176286
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
239.75 | 3.30 | 3.30 |
283.80 | 3.05 | 3.05 |
269.77 | 2.61 | 2.61 |
269.77 | 2.61 | 2.61 |
222.29 | 1.01 | 1.01 |
222.29 | 1.01 | 1.01 |
255.74 | 2.27 | 2.27 |
255.75 | 2.27 | 2.27 |
221.30 | 1.62 | 1.62 |
239.29 | 1.76 | 1.76 |
300.20 | 2.38 | 2.38 |
235.33 | 1.93 | 1.93 |
251.33 | 1.63 | 1.63 |
266.30 | 1.53 | 1.53 |
239.29 | 1.76 | 1.76 |
255.75 | 2.27 | 2.27 |
235.33 | 1.93 | 1.93 |
251.33 | 1.63 | 1.63 |
257.28 | 1.90 | 1.90 |
290.19 | 2.93 | 2.93 |
257.28 | 1.90 | 1.90 |
290.19 | 2.93 | 2.93 |
297.40 | 3.29 | 3.29 |
347.46 | 4.44 | 4.44 |
347.46 | 4.44 | 4.44 |
269.77 | 2.66 | 2.66 |